Our new Very clear+ tissue clearing strategy is the one process that delipidates samples without having alter in morphology and with minimum influence on structural integrity.
Our switch-essential SmartBatch+ process brings together electrophoretic tissue clearing and immunolabeling into just one superior-throughput machine.
Antibodies may possibly just take months to diffuse by way of just a few millimeters of tissue, by using a steep labeling gradient from floor to Main.
Jogging the CLI straight from a Gradle undertaking will not be now supported. A distribution needs to be established by using gradlew :j2d-cli:distZip to produce a zip file that contains almost everything necessary to run.
SE makes use of a rotational electric field to disperse really electromobile molecules (which include antibodies or surfactant micelles) in the course of a porous sample devoid of detrimental electrically charged structures throughout the tissue. This allows two-four working day clearing of intact organs,
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Megatome is often a novel microtome that permits for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays megatomi.com of animal organs, to intact human brain hemispheres – with small tissue injury and knowledge reduction.
eFLASH is really a rapid tissue labeling technique which allows for uniform entire-organ staining in twenty rounds of labeling.
The SmartSPIM light-weight sheet microscope offers unparalleled resolution and acquisition velocity during intact tissue volumes, although its modular structure permits you to enhance and personalize individual elements.
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SHIELD avoids the variability of hydrogel embedding and the knowledge reduction from PFA preservation, preserving specimens for numerous rounds of processing.
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Our novel SHIELD tissue preservation approach varieties intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.